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Wake Forest University

Publications

    Invited Articles and Reviews

  1. Grabbing the cat by the tail: manipulating molecules one by one. Bustamante, C., Macosko, J.C., & Wuite, G.J.L. Nature Reviews Molecular and Cell Biology 1, 130-136 (2000).

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    Peer-Reviewed Publications

  2. Fewer active motors per vesicle may explain slowed vesicle transport in chick motoneurons after three days in vitro. Macosko, J.C., Newbern, J.M., Rockford, J., Chisena, E.N., Brown, C.M., Holzwarth, G., and Milligan C.E. Brain Research, In Press, Accepted Manuscript, Available online 20 March 2008
  3. Speckling Improves Tracking in Gliding Assays. Chisena, E.N. Wall, R.A., Macosko, J.C., and Holzwarth, G. Physical Biology, 4, 10-5 (2007)
  4. Stepping Statistics of Single HIV-1 Reverse Transcriptase Molecules during DNA Polymerization Ortiz, T.P., Marshall, J.A., Meyer, L.A., Davis, R.W., Macosko, J.C., Hatch, J., Keller, D.J. & Brozik, J.A. Journal of Physical Chemistry B 109,16127 – 16131 (2005)
  5. Closing of the Fingers Domain Generates Motor Forces in the HIV Reverse Transcriptase. Lu, H., Macosko, J.C., Habel-Rodriguez, D., Keller, R.W., Brozik, J.A. & Keller, D.J.  Journal Biological Chemistry 24, 54529-54532 (2004)
  6. Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization. Poirier, M.A., Li H., Macosko, J.C., Cai, S., Amzel, M., Ross, C.A., Journal of Biological Chemistry. 43, 41032-41037. (2002)
  7. The 1-127 HA2 construct of influenza virus hemagglutinin induces cell-cell hemifusion. Leikina E., LeDuc D.L., Macosko J.C. Epand, R., Epand, R., Shin ,Y.K., Chernomordik, L.V., Biochemistry 40, 8378-8386 (2001).
  8. 15N NMR study of the ionization properties of the influenza virus fusion peptide in zwitterionic phospholipid dispersions. Zhou Z., Macosko J.C., Hughes, D.W., Sayer, B.G., Hawes, J., Epand, R.M..Biophysical Journal 78, 2418-2425 (2000).
  9. A novel 5' displacement spin-labeling technique for electron paramagnetic resonance spectroscopy of RNA. Macosko, J.C., Pio, M.S., Tinoco, I. Jr, Shin, Y.K. RNA Journal 9, 1158-1166 (1999).
  10. The ectodomain of HA2 of influenza virus promotes rapid pH dependent membrane fusion. Epand, R.F., Macosko, J.C., Russell, C.J., Shin, Y.K., Epand, R.M., Journal of Molecular Biology 286, 489-503 (1999).
  11. The synaptic SNARE complex is a parallel four-stranded helical bundle. Poirier, M.A., Xiao, W., Macosko, J.C., Chan, C., Shin ,Y.K., Bennett, M.K., Nature Strucural. Biology 5, 765-769 (1998)
  12. The mechanism for low-pH-induced clustering of phospholipid vesicles carrying the HA2 ectodomain of influenza hemagglutinin. Kim, C.H., Macosko, J.C., & Shin, Y.-K. Biochemistry 37, 137-144 (1998)
  13. The membrane topology of the fusion peptide region of influenza hemagglutinin determined by spin-labeling EPR. Macosko, J.C., Kim, C.H., Shin. Y.K. Journal of Molecular Biology 267, 1139-1148 (1997)
  14. On the dynamics and conformation of the HA2 domain of the influenza virus hemagglutinin. Kim, C.H., Macosko, Yu, Y.G., Shin, Y.K., Biochemistry 35, 5359- 5365 (1996).

    15. Patents and Patent Applications

  15. Macosko, J.C. & Olsson, C., Centrifugal Force Molecular Sensor, UC Case No. B02-037.
  16. Macosko, J.C., Kim, C.-H., & Shin, Y.-K. Influenza Drug Target, UC Case No. B98-060.
  17. Macosko, J.C., Guthold, M., Lab-on-Bead™ encoding methods that enhance biological technologies, WFU No. 07-56

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