NEUROSCIENCE 300

NEUROSCIENCE SEMINARS. Spring 2009

COORDINATOR: WAYNE SILVER (OFFICE: 15 WINSTON, PHONE: 5920)

e-mail:  silver@wfu.edu

9:30 - 10:45 Tuesday and Thursday in Winston Hall Room 234

Readings: Found on Blackboard

 

CLICK (or hit control and then click) ON THE SPEAKER’S NAME TO GO TO HIS/HER WEB SITE.

 

Date                 Host and Speaker             Student                     Title  

 

Th Jan       15

Wayne Silver Introduction

 

 

Tu             20

Jim Schirillo (Psych)

 

Estrogen and the Brain: What's The

Th             22

Mary Lou Voytko

 

Buzz?

Tu             27

Visit to Targacept

 

Effects of nicotinics on learning and

Th             29

Sharon Letchworth

 

memory

Tu Feb      3

Bill Conner (Bio)

Amanda

Mesenchymal stem cells: emerging therapy

Th             5

Martin Childers

 

for Duchenne muscular dystrophy

Tu             10

Wayne Silver (Bio)

Emily

Radiation-induced Brain Injury:  

Th             12

Mike Robbins

 

Mechanisms and Treatment

Tu             17

Dale Dagenbach (Psych)

Afton

Effects of training on the representation

Th             19

Christos Constantinidis

 

of working memory in brain activity

Tu             24

Jim Schirillo (Psych)

 

Can Shadows Control

Th             26

Jim Schirillo

 

Microsaccades?

Tu Mar     3

Wayne Pratt (Psych)

Sam

Animals Models of Addiction

Th             5

Dave Roberts

 

 

Tu            10

SPRING BREAK

 

 

Th            12

SPRING BREAK

 

 

Tu             17

Wayne Pratt (Psych)

 

Examining neural circuits that promote feeding beyond need

Th             19

Wayne Pratt

 

(or, the neurobiology of eating dessert)

Tu             24

Wayne Silver (Bio)

Brian

Rank-order-selective neurons form a basis

Th            26                3

Emilio Salinas

 

set for generating sequences of motor actions

Tu             31

Erik Johnson (Bio)

 

Stressed-out flies: Conservation

Th Apr      2

Erik Johnson

 

of neuroendocrine circuits

Tu             7

Susan Fahrbach (Bio)

Colston

Nonhuman Primate

Th             9

Paul Czoty

 

Models of Addiction

Tu             14

Janine Jennings (Psych)

Ae’Jay

Now you see it, now you don't - now you do!

Th             16

John McHaffie

 

Cross-modal rehabilitation in an animal model of visual hemineglect

Tu             21

Anita McCauley (Bio)

 

 

Th             23

Chris Turner

 

A Perfect Storm in a Baby's Brain

Tu             28

Jim Toole

Silver

 


Grading: 

 

Papers: 90% You will be responsible for writing a 2-3 page summary of each seminar. In this summary provide

  1. a concise statement of the question being addressed (20 points)
  2. a concise statement of the results obtained. (20 points)
  3. a brief description of the methods used to address the question. (20 points)
  4. a discussion of how does this study advance our knowledge of this subject? What is the “Big Picture”? (20 points)

 

The quality of your writing and your scientific accuracy are each worth 10 points.

 

You will be allowed to drop your lowest paper grade.

 

Participation: 10%   Each student will be assigned to one or more of the seminars, and along with the Neuroscience Faculty Host, will be responsible for leading the Tuesday discussions. Your participation grade is based on your contributions to class discussions as well as how you “lead” your assigned discussion. Please contact the Faculty Host before your presentation.

 

READINGS

 

Mary Lou Voytko

Luine VN. (2008) Sex steroids and cognitive function. J Neuroendocrinol. Jun;20(6):866-72. Epub 2008 Jun 1.

Sharon Letchworth

Ronald Bailey, The Battle for Your Brain: Science is developing ways to boost intelligence, expand memory, and more. But will you be allowed to change your own mind? February 2003 Print Edition

 

Martin Childers

Markert, C.,  Atala, A, Cann, J.K., Christ, G., Furth, M, Ambrosio, F., and Childers, M.K. Mesenchymal Stem Cells: Emerging Therapy for Duchenne Muscular Dystrophy. Unpublished Review.  

 

Mike Robbins

Zhao, W., Payne, V., Tomassi, E., Diz, D.I., Hsu, F-C, Robbins, M.E. (2007)Administering the peroxisomal proliferator-activated receptor g agonist pioglitazone during fractionated brain irradiation prevents radiation-induced cognitive impairment. Int J Radiat Oncol Biol Phys 67,

6-9.

Robbins ME, Payne V, Tommasi E, Diz DI, Hsu FC, Brown WR, Wheeler KT, Olson J, Zhao W. (2008) The At(1) Receptor Antagonist, L-158,809, Prevents Or Ameliorates Fractionated Whole-Brain Irradiation-Induced Cognitive Impairment. Int J Radiat Oncol Biol Phys. Dec 10. [Epub ahead of print]

Christos Constantinidis

Meyer T, Xue-Lian Qi X-L, and Constantinidis C. (2007) Persistent Discharges in the Prefrontal

Cortex of Monkeys Naıve to Working Memory Tasks. Cerebral Cortex 17: i70--i76

 

Jim Schirillo

Kowler E and Steinman RM . (1980) Transient stimulation does not aid visual search: implications for the role of saccades. Percept Psychophys. Jan;27(1):1-10

Martinez-Conde S, Macknik SL, Hubel DH. (2004) The role of fixational eye movements in visual perception. Nat Rev NeurosciMar;5(3):229-40.

Pritchard RM. (1961) Stabilized images on the retina. Sci Am. Jun;204:72-8.

Dave Roberts

Roberts DCS, Morgan D, Liu Y (2007) How to make a rat addicted to cocaine.  Progress in Neuro-Psychopharm & Biol Psychiat. 31: 1614-1624.

 

Wayne Pratt

Will MJ, Pratt WE, Kelley AE. Pharmacological characterization of high-fat feeding induced by opioid stimulation of the ventral striatum. Physiol Behav. 2006 Sep 30;89(2):226-34.

Berthoud HR, Morrison C. The brain, appetite, and obesity. Annu Rev Psychol. 2008;59:55-92

Emilio Salinas

Shima K, Tanji J (2000) Neuronal activity in the supplementary and presupplementary motor areas for temporal organization of multiple movements. J Neurophysiol 84(4):2148-60.

 

Erik Johnson

Lightman SL. (2008). The neuroendocrinology of stress: a never ending story. J Neuroendocrinol. 20(6):880-4

 

Paul Czoty

 

Nader MA, Czoty PW. PET imaging of dopamine D2 receptors in monkey models of cocaine abuse: genetic predisposition versus environmental modulation. Am J Psychiatry. 2005, 162:1473-82.

 

John McHaffie

Rauschecker JP, Korte M. Auditory compensation for early blindness in cat cerebral cortex. J Neurosci. 1993 Oct;13(10):4538-48.

Chris Turner

Turner CP, Miller R, Smith C, Brown L, Blackstone K, Dunham SR, Strehlow R, Manfredi M, Slocum P, Iverson K, West M, Ringler SL, Berry ZC. (2007) Widespread neonatal brain damage following calcium channel blockade. Dev Neurosci.;29(3):213-31

Jim Toole

 

Poirier FE. Understanding Human Evolution Prentice Hall, Englewoodcliffs, NJ, 1993, 124-136.

 

Falk D. Hominid brain evolution: Looks can be deceiving. Science. 1998, 280:1714.

 

Conroy GC, Weber GW, Seidler H, Tobias PV, Kane A, and Brunsden B. Endocranial capacity in an early hominid cranium from Sterkfontein, South Africa. Science. 1998, 280: 1730-1731.