DEPARTMENT OF CHEMISTRY
PROFESSIONAL ACTIVITIES SUMMARY
FOR JULY 1, 1998 TO JUNE 30, 1999

 

I. Publications, Performances, Exhibits

 

Colyer, Christa L.

L.L. Shultz-Lockyear, C.L. Colyer, Z. H. Fan, K.I. Roy, and D.J. Harrison, "Effects of injector geometry and sample matrix on injection and sample loading in integrated capillary electrophoresis devices," Electrophoresis, 1999, 20, 529-538.

N.H. Bings, C.D. Skinner, C. Wang, C.L. Colyer, D.J. Harrison, J.Li, and P. Thibault, "Coupling electrospray mass spectrometry to microfluidic devices with low dead volume connections," in: D.J. Harrison and A. van den Berg (editors), Proceedings of the uTAS '98 Workshop (Banff, Canada), Kluwer Academic Publishers, Dordrecht, 1998, pp. 141-144.

L.L. Shultz-Lockyear, C.L. Colyer, K.I. Roy, and D.J. Harrison, "Sample matrix effects on injection and sample loading in integrated capillary electrophoresis devices," in: D.J. Harrison and A. van den Berg (editors), Proceedings of the uTAS '98 Workshop (Banff, Canada), Kluwer Academic Publishers, Dordrecht, 1998, pp. 169-172.

 

Haefner, Steven C.

Two DiphenylFormamidinato Compounds of the Quadruply-bonded Re26+ Core. F. A. Cotton, L. M. Daniels, S. C. Haefner Inorg. Chim. Acta , 1999, 9, 285, 149-151

 

Hinze, Willie L.

"Characterization and Evaluation of d-(+)-Tubocurarine Chloride as a Chiral Selector for Capillary Electrophoretic Enantioseparations", Usha B. Nair, Daniel W. Armstrong and Willie L. Hinze, Analytical Chemistry, 70 (1998) 1059-1065.

 

Jones, Bradley T.

J.D. Batchelor, S.E. Thomas, B.T. Jones, "Determinatiuon of Cadmium with a Portable, Battery-Powered Tungsten Coil Atomic Absorption Spectrometer," Appl. Spectrosc., 1998, 52, 1086-1091.

K.A. Wagner, K.E. Levine, B.T. Jones, "A simple, low-cost, multielement atomic absorption spectrometer with a tungsten coil atomizer," Spectrochim. Acta Part B, 1998, 53, 1507-1516.

K.E. Levine, K.A. Wagner, B.T. Jones, "A low-cost, modular electrothermal vaporization system for inductively coupled plasma atomic emission spectrometry," Appl. Spectrosc., 1998, 52, 1165-1171.

J.D. Batchelor, B.T. Jones, "Development of a Digital Micromirror Spectrometer for Analytical Atomic Spectrometry," Anal. Chem. 1998, 70, 4907-4914.

K.E. Levine, J.D. Batchelor, C.B. Rhoades, Jr., B.T. Jones, "Evaluation of a high-pressure, high-temperature microwave digestion system," J. Anal. At. Spectrom. 1999, 14, 49-59.

K.D. Besecker, C.B. Rhoades, Jr., B.T. Jones, K.W. Barnes, "A Simple Closed-Vessel Nitric Acid Digestion Method for a Polyethylene/polypropylene Polymer Blend," Atomic Spectroscopy, 1998, 19(6), 193-197.

M.M. Daniel, J.D. Batchelor, C.B. Rhoades, Jr., B.T. Jones, "The effect of digestion temperature upon the extent of matrix decomposition using a high pressure asher," Atomic Spectroscopy, 1998, 19(6), 198-203.

K.A. Wagner, J.D. Batchelor, B.T. Jones, "A Rowland Circle, multielement graphite furnace atomic absorption spectrometer," Spectrochim. Acta Part B, 1999, 53, 1805-1813.

 

King, S. Bruce

King, S.B.; Nagasawa, H.T. "Chemical Approaches Toward the Generation of Nitroxyl (HNO)", In Methods in Enzymology; Packer, L, Ed.; Academic Press: San Diego, 1998, Vol. 301, Chapter 22.

Xu, Y.; Mull, C.D.; Bonifant, C.L.; Yasaki, G.; Palmer, E.C.; Shields, H.; Ballas, S.K.; Kim-Shapiro, D.B.; King, S.B. "Nitrosylation of Sickle Cell Hemoglobin by Hydroxyurea," J. Org. Chem., 1998, 63, 6452-6453.

 

Kondepudi, Dilip

Modern Thermodynamics: From heat engines to dissipative structures (John Wiley, New York, 1999) Second Printing, October 1998.

"Formation of the Intermediate, Aquohydroxobis (Ethylenediamine) Cobalt (III) Complex, in the Preparation of Cis-[CoBr(NH3)(en)2]Br2 ..... "(Co-author: K. Asakura, K. Inoue, and S. Osanai) J. Coord. Chem 46 (1998) 159-164.

"Mechanism of Chiral Asymmetry Generation by Chiral Autocatalysis in the Preparation of Chiral Octahedral Cobalt Complex" (Co-authors: K. Asakura, R. Martin) Chirality 10 (1998)343-348.

"Kinetics of Chiral Resolution in Stirred Crystallization of Amino Acids" (Co-authors: T. Buhse, and B. Hoskins) Chirality 11 (1999) 342-348.

"Chiral Symmetry Breaking in Stirred Crystallization of Binaphthyl Melt" (Co-authors: K. Asakura and J. Laudadio) J. Am. Chem. Soc. 121 (1999)1448-1451.

 

Lachgar, Abdessadek

E.V.Anokhina, M.W.Essig, A.Lachgar, "Ti2Nb6Cl14O4: A Unique 2D-1D Network Combination in Niobium Cluster Chemistry" Angew. Chem. Int. Ed. Engl. 1998, 37, 522-525.

X. Tang and A. Lachgar, "The Missing Link: Synthesis, Crystal Structure, and Thermogravimetric Studies of InPO4H2O" Inorg. Chem. 1998, 37, 6181-6185

 

Manderville, Richard A.

Borah,S.; Melvin, M.S.; Lindquist, N.; Manderville, R.A. Copper-Mediated Nuclease Activity of a Tambjamine Alkaloid. J. Am. Chem. Soc., 1998, 120, 4557-4562.

Ardus, J.A.; Gillman, I.G.; Manderville, R.A. On the Role of Iron and Copper in DNA Cleavage by Ochratoxin A. Structure-Activity Relationships in Metal Binding and Copper-Mediated DNA Cleavage. Can. J. Chem., 1998, 76, 907-918.

Gillman, I.G.; Day, C.S.; Manderville, R.A. Stepwise Formation of a Nonsymmetric Dinuclear Copper Complex of Ochratoxin A. Inorg. Chem., 1998, 37, 6385-6388.

Gillman, I.G.; Yezek, J.M.; Manderville, R.A. Ochratoxin A Acts as a Photoactivatable DNA Cleaving Agent. Chemical Commun., 1998, 647-648.

Dust, J.M.; Manderville, R.A. Carbon Versus Oxygen Nucleophilic Selectivity in the Reaction of the Aryloxide Ions, 2,6- and 3,5-Di-tert-butylphenoxide, with the 2-[(nitro)xaryl]-4,6-dinitrobenzotriazole 1-Oxide Series of Super-Electrophiles. Stereoelectronic Factors on C-7 Meisenheimer Complex Formation Versus C-1 SNAr Displacement. Can J. Chem., 1998, 76, 662-671.

 

Noftle, Ronald E.

S.K. Ritter and R.E. Noftle, "Cleavage of substituents upon oxidative polymerization of substituted thiophenes" Inorg. Chimica Acta, 1999, 232-237.

P.M. Narula and R.E. Noftle, "Investigation oof the lifetimes of some pyrrole species by rapid scan cyclic voltammetry and double potential step techniques" J. Electroanal. Chem., 1999, 464, 123-127.

S.K. Ritter, B.K. Hill, M.A. Odian, J. Dai, R.E. Noflte, G.L. Gard, "Synthesis and characterization of thiophenes with fluorinated substituents" J. Fluorine Chem., 1999, 93, 73-79.

M.A. Odian and R.E. Noflte, "Preparation and oxidative polymerization of 3-Thieylperfluoroacylimides," J. Fluorine Chem., 1998, 92, 129-133.

 

Swofford, Robert L.

"Inclusion Complexes of N-Benzoyl-D-leucine and N-Benzoyl-L leucine with b -Cyclodextrin by Raman Spectroscopy", Robin Spivey and Robert L. Swofford, Appl. Spectrosc. 53, 435 (1999).

 

Welker, Mark E.

Transition-Metal Mediated 2-Alkylidene Cyclobutanone Synthesis. N. Ariane Vinson, Cynthia S. Day, Mark E. Welker*, Ilia Guzei, and Arnold L. Rheingold. Organometallics, 1999, 18, 1824.

Transition-Metal Mediated Exo Selective and Enantioselective Diels-Alder Reactions for the Preparation of Octalones with Unusual Stereochemistries. Reactions of 2-Cobaloxime Substituted 1,3-Dienes with Cyclohexenone in Enantioselective Lewis Acid Catalyzed [4 + 2] Cycloadditions. B. Matthew Richardson, Cynthia S. Day and Mark E. Welker*. Journal of Organometallic Chemistry, 1999, 577, 120.

Reactions of Transition-Metal Cyclopropyl and h1-Allyl Complexes with Sulfur Dioxide and Disulfur Monoxide. Brittany L. Hayes and Mark E. Welker*. Organometallics, 1998, 17, 5534.

Transition-Metal Mediated Dihydropyran Syntheses. Exo Selective Hetero Diels-Alder Reactions of Cobaloxime Dienyl Complexes with Aldehydes. Torrey A. Adams, Mark E. Welker*, and Cynthia S. Day. J. Org. Chem. 1998, 63, 3683.

Reactions of Transition-Metal h1-Propargyl and h1-Allenyl Complexes with Sulfur Dioxide and Transition-Metal-Carbon Bond Cleaving Reactions of the Cycloadducts Which Yield Cyclic Sulfenate Esters. Allison L. Hurley, Mark E. Welker*, and Cynthia S. Day. Organometallics, 1998, 17, 2832.

 

 

II. Papers and Presentations

Colyer, Christa L.

E.D. Moody, P.J. Viskari, and C.L. Colyer, "Non-covalent labeling of proteins with indocyanine green: A study by capillary electrophoresis with diode laser-induced fluorescence detection," 9th Annual Frederick Conference on Capillary Electrophoresis, Frederick, MD: October 19-21, 1998.

P.J. Viskari, E.D. Moody, and C.L. Colyer, "Allophycocyanin: a study by capillary electrophoresis," 9th Annual Frederick Conference on Capillary Electrophoresis, Frederick, MD: October 19-21, 1998.

E.D. Moody, P.J. Viskari, and C.L. Colyer (Symposium Presider), "Diode lasers for detection in capillary electrophoresis," 50th Southeastern Regional Meeting of the American Chemical Society, Research Triangle Park, NC: Nov. 4-7, 1998.

C.L. Colyer, "Microchips and conventional capillaries for capillary electrophoresis with laser-induced fluorescence detection," University of North Carolina at Greensboro, Nov. 20, 1998.

C.L. Colyer, "Microchips and conventional capillaries for capillary electrophoresis with laser-induced fluorescence detection," Appalachian State University, Boone NC: March 26, 1999.

E.D. Moody and C.L. Colyer, "The Non-Traditional Application of Indigo Carmine as a Fluorescent Tag," 16th Triangle Chromatography Symposium and Instrument Exhibit, Raleigh, NC: May 13, 1999.

P.J. Viskari, E.D. Moody, and C.L. Colyer, "The Use of Allophycocyanin as a Fluorescent Probe in Capillary Electrophoresis with Diode Laser Induced Fluorescence Detection," 16th Triangle Chromatography Symposium and Instrument Exhibit, Raleigh, NC: May 13, 1999.

C.L. Colyer, "Case Study in Chemistry," NSF Case Studies in Science Workshop, SUNY-Buffalo, Buffalo, NY: June 7-11, 1999.

P.J. Viskari, E.D. Moody, and C.L. Colyer, "A study of allophycocyanin by capillary electrophoresis with diode laser-induced fluorescence detection," 21st International Symposium on Capillary Chromatography and Electrophoresis, Park City, Utah: June 20-24, 1999

 

Haefner, Steven C.

"Synthesis of Linear Transition Metal Clusters Supported by Pyridyl Substituted Formamidinates." S. C. Haefner, Elizabeth E. Scott and C. S. Day, 50th ACS Southeast Regional Meeting, Research Triangle Park, NC, 11/98.

"Synthesis and characterization of a new full solvated dimolybdenum cation that possesses a Mo-Mo quadruple bond." S. C. Haefner and C. S. Day, 217th ACS National Meeting, Anaheim, CA, 3/99.

 

Hinze, Willie L.

Short Course on "Enantiomeric Separations", XXIII Latin American Chemical Congress and 6th Caribbean Environmental Chemical Conference, July 27, 1998, Westin Rio Mar Hotel, Rio Grande, Puerto Rico.

"Intramolecular Micelle-Mimetic Ionenes as Luminescence Enhancement Agents", [Bernardo Moreno, Frank H. Quina, Willie L. Hinze], 25th Conference of the Federation of Analytical Chemistry and Spectroscopy Societies, October 13, 1998, Austin, Texas.

"Separations Using Novel Surfactant and Related Molecules", 217th American Chemical Society National Meeting, March 24, 1999, Anaheim, California.

 

Jones, Bradley T.

B.T. Jones, J.D. Batchelor, A. Salido, K.E. Levine, M.M. Daniel, K.A. Wagner, "Simultaneous determination of Pb, Cu, Cd, and Cr in drinking water by AAS and XRF spectrometry," Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Austin, TX, October 1998. Invited Lecture.

A. Salido, B.T. Jones, "Determination of Pb in blood by W coil AAS," Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Austin, TX, October 1998.

K.E. Levine, J.D. Batchelor, A. Salido, B.T. Jones, "An inexpensive, modular tungsten coil electrothermal vaporization system for a commercially available ICP-OES," Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Austin, TX, October 1998.

J.D. Batchelor, B.T. Jones, "A digital micromirror device spectrometer for atomic spectroscopy," Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Austin, TX, October 1998.

 

King, Angela Glisan

"Application of Interactive Web Tools in Teaching Redox Chemistry," Yue-Ling Wong and Angela G. King, Interactive Multimedia Electronic Journal, Volume 1, Issue 1.

"Development and Evaluation of an On-line Redox Tutorial," Angela G. King and Yue-Ling Wong, Biennial Conference on Chemical Education, Waterloo, Canada, August 12, 1998.

"Impact of Technology on Teaching Chemistry," Best-Practices Conference, International Center for Computer Enhanced Learning, Winston-Salem, NC, January 8, 1999.

"Track Leader," Catalyst Conference, International Center for Computer Enhanced Learning, Winston-Salem, NC, January 15, 1999.

 

King, S. Bruce

The Oxidative Stress and Free Radical Faculty Seminar Series, National Institute of Environmental Health Sciences, Research Triangle Park, NC, December 3, 1998

Chemistry Department Seminar, Elon College, November 20, 1998

Plenary Speaker, Third International Conference on the Biochemistry and Molecular Biology of Nitric Oxide, University of California, Los Angeles, July 15, 1998

Xu, Y.; Bonifant, C.L.; King, S.B. "Chemical and Biological Oxidation of N-Hydroxyureas with Nitroxyl Production," Gordon Research Conference on Nitric Oxide, Ventura, CA, February 7-12, 1999.

Atkinson, R.N.; King, S.B. "Syntheses and Evaluation of New Imidazole Containing Inhibitors of Nitric Oxide Synthase," Gordon Research Conference on Nitric Oxide, Ventura, CA, February 7-12, 1999.

Xu, Yueping, King, S.B. "Nitroxyl Release From C-Nitrosoformamides," Abstract of Papers, 50th Southeast Regional Meeting of the American Chemical Society, Raleigh, NC, American Chemical Society, Washington, D.C. 1998, ORGN 425.

Ware, R.W., Jr.; King, S.B. "N-Phosphinoylnitroso Compounds as New N-O Heterodienophiles and Nitroxyl Releasing Agents," Abstract of Papers, 50th Southeast Regional Meeting of the American Chemical Society, Raleigh, NC, American Chemical Society, Washington, D.C. 1998, ORGN 401.

Atkinson, R.N.; Ichimori, K.; Stuehr, D.J.; King, S.B. "Synthesis and Evaluation of New Sulfur Containing L-Arginine Derived Inhibitors of Nitric Oxide Synthase," Abstract of Papers, 216th National Meeting of the American Chemical Society, Boston, MA, American Chemical Society, Washington, D.C. 1998, MEDI 26.

Atkinson, R.N.; King, S.B. "Synthesis and Biochemical Evaluation of New Imidazole Containing Compounds Designed to Interact with Nitric Oxide Synthase," Abstract of Papers, 216th National Meeting of the American Chemical Society, Boston, MA, American Chemical Society, Washington, D.C. 1998, MEDI 85.

Ware, R.W., Jr.; King, S.B. "N-Phosphinoylnitroso Compounds as New N-O Heterodienophiles and Nitroxyl Releasing Agents," Abstract of Papers, 216th National Meeting of the American Chemical Society, Boston, MA, American Chemical Society, Washington, D.C. 1998, ORGN 413.

 

Kondepudi, Dilip

"The Enigma of Chiral Asymmetry" Physics Colloquium, University of Maryland (College Park) 2 February, 1999.

Workshop: "Cells in Space Flight: Past Present and Future" organized by the Marine Biological Laboratories, Woods Hole, MA. 7-8 March, 1999.

American Chemical Society, National Meeting, Anaheim, CA. Awards Symposium, 23-25 March, 1999

 

Lachgar, Abdessadek

E.V.Anokhina, M.W.Essig, C.S. Day, A.Lachgar, "Design, Synthesis and Structural Studies of Open-Framework Materials in Niobium Oxohalide Cluster Chemistry" Abstract #262, Annual Meeting of American Crystallographic Association, Arlington, VA July 19-23, 1998.

Michael W. Essig, Ekaterina Anokhina, Cynthia S. Day, Abdessadek Lachgar, "Structural Studies of the Effects of Dopping the Cluster Compound Ti2Nb6Cl14O4 with In+ and Tl+ Ions" Abstract #263, Annual Meeting of American Crystallographic Association, Arlington, VA July 19-23, 1998.

X. Tang and A. Lachgar, "Hydrothermal Synthesis and Structural Studies of Open Frameworks Indium Hydrogen Phosphates and Hydrogen Arsenates" Abstract #233, Annual Meeting of American Crystallographic Association, Arlington, VA July 19-23, 1998.

E.V.Anokhina, M.W.Essig, C.S. Day, A.Lachgar, "Synthesis and characterization of a Chevrel phase analogue in reduced niobium titanium oxides" Gordon Research Conference on Solid State Chemistry, New Hampshire, July 26-31, 1998.

A. Lachgar and E.V. Anokhina, "Synthesis and crystal structure of a layered niobium oxohalide" Gordon Research Conference on Solid State Chemistry, New Hampshire, July 26-31, 1998.

A. Lachgar, E. V. Anokhina, M. W. Essig, C. S. Day "Rational Design of Oxo-Halide Compounds: The Mixed-Ligand Approach to the Synthesis of Open-Framework Niobium Oxo-Halide Cluster Compounds", Symposium on Rational Synthesis of Solid-State Materials, SERMACS, Raleigh, NC, November 4-7, 1998.

 

Manderville, Richard A.

R. A. Manderville, M. S. Melvin, M. B. Consilivio, "Structure-Activity relationships in copper-mediated DNA cleavage by tambjamines alkaloids and related polypyrroles", poster presented at

216th ACS National Meeting, August 23-27, 1998, Boston, MA.

G. Gillman and R. A. Manderville, "Copper-mediated DNA cleavage by ochratoxin A", 20 min oral presentation at 216th ACS National Meeting, August 23-27, 1998, Boston, MA.

I.G. Gillman and R.A. Manderville, "Oxidation of Ochratoxin A by Iron Containing Systems: Models for Cytochrome P-450 Activation", poster presented at SERMACS 1998, November 4-7, Research Triangle Park, NC.

M.S. Melvin, M.B. Consilvio and R.A. Manderville, "Synthesis and Nuclease Activity of Bipyrrole Natural Products Related to the Tambjamine Alkaloids", poster presented at SERMACS 1998, November 4-7, Research Triangle Park, NC.

Invited Seminar, "DNA Cleavage by Tambjamine Alkaloids" Agnes Scott College, 141 East College Avenue, Atlanta/Decatur, GA 30030, November 16, 1998.

Invited Seminar, "Oxidative DNA Damage by Ochratoxin A" Furman University, Greenville, SC, January 28, 1999.

Invited Seminar, "Oxidative DNA Damage by Ochratoxin A" University of Central Florida, Orlando, FL, March 1, 1999.

Invited Seminar, "Oxidative DNA Damage by Ochratoxin A" George Washington University, 725 21st St. N.W., Washington, D.C. 20052, April 9, 1999.

 

Noftle, Ronald E.

J. Dai and R.E. Noftle, "New thiophene monomers containing fluorinated groups," 14th Winter Conference on Fluorine Chemistry, St. Petersburg, Florida, January 17-22, 1999.

J. Dai and R.E. Noflte, "Synthesis and characterization of thiophenes bearing imide groups," Southeastern Regional ACS Meeting, Raleigh, NC, November 4-7, 1998.

M.W. Calcutt, R.E. Noftle, R.A. Manderville, I.G. Gillman, "Anodic oxidation of ochratoxin A and the electrochemical properties of its oxidatively produced derivatives," Southeastern Regional ACS Meeting, Raleigh, NC, November 4-7, 1998.

 

 

 

 

III. Editorships, Offices,and Consultancies

 

Hinze, Willie L.

Editorial Review / Advisory Boards of the following scientific journals: Analytical Letters, Journal of Liquid Chromatography, and Talanta

National Institutes of Health Special Study Section on Small Business Innovative Research Grant and Small Business Technology Transfer Grant Applications, November 11-13, 1998 and March 14-16, 1999, Washington, DC

 

Jones, Bradley T.

Consultant, R.J. Reynolds Tobacco Company

Consultant, Leeman Labs, Inc.

Panel reviewer for EPA Small Business Innovative Research Award.

 

King, Angela Glisan

Editor, Interactive Multimedia Electronic Journal.

Chair, Women Chemists Committee, American Chemical Society Local Section.

 

Kondepudi, Dilip

Editorial Board of Chirality

 

Noftle, Ronald E.

Alternate Councilor, Division of Fluorine Chemistry, American Chemical Society.

 

Welker, Mark E.

Panel reviewer for NSF Career Award.

 

IV. External Grants Received

Hinze, Willie L.

$5,000 "ACS Award Symposium in Chromatography," University of Missouri-Rolla,

 

Jones, Bradley T.

$70,000 "An ICP Spectrometer for Instrument Development" Leeman Labs, Inc.,.

$20,000 "A Graphite Furnace Atomic Absorption Spectrometer for Undergraduate Education" Perkin-Elmer Corp.

$21,000 "Development of Quatro, a 4-element atomic absorption spectrometer" Leeman Labs, Inc.

$96,250 "An Inexpensive reliable blood-Pb Analyzer" NIH-STTR.

 

King, Angela Glisan

$485 "Saturday Science Pen Pals" Association for Women in Science.

$228,305 "Summer Program for Faculty Adoption of Technology." Culpeper Foundation.

 

King, S. Bruce

$5000 "Development of New Asymmetric Transition Metal Based N-O Heterodienophiles," Glaxo-Wellcome Undergraduate Research Fellowship.

 

Manderville, Richard A.

$20,000 "Synthesis of Tambjamine Alkaloids and Polypyrroles as DNA Sensors." American Chemical Society-Petroleum Research Fund, ACS-PRF# 33043-G.

$40,000 "Development of Tambjamine Alkaloids and Related Polypyrroles as DNA-Targeting Anticancer Agents." North Carolina Biotechnology Center, #9805-ARG-0012.

 

Welker, Mark E.

$60,000 "Transition-Metal Mediated Cyclobutenone Synthesis," Petroleum Research Fund, 33380-AC1.

$69,760 "Exploratory Diels-Alder Reactions of Epoxybutene and its Derivatives" Eastman Chemical Company.

$6500 "Summer Faculty Fellowship for Anne G. Glenn" Petroleum Research Fund.