DEPARTMENT OF CHEMISTRY
PROFESSIONAL ACTIVITIES SUMMARY
FOR JULY 1, 1997 TO JUNE 30, 1998



 

I. Publications, Performances, Exhibits
 
 

Colyer, Christa L.

(with Mangru, S. D. and Harrison, D. J.) "Microchip-based capillary electcrophoresis of human serum proteins," Journal of Chromatography A, 781 (1997) 271-276.

(with Tang, T., Chiem, N., Harrison, D.J.) "Clinical potential of microchip capillary electrophoresis systems," Electrophoresis, 18 (1997) 1733-1741.
 
 

Haefner, Steven C.

(with Cotton, F.A., Sattelberger, A.P.) "Metal-Metal Multiply-Bonded Complexes of Technetium..6. Reductive cleavage of the Tc=Tc Triple Bond in [TC2(CH3CN)10][BF4]4." Inorg. Chim. Acta (1997).

(with Cotton, F.A., Sattelberger, A.P.) "Metal-metal Multiply-Bonded Complexes of Technetium.7. Oxidative Decomposition of Tetrachlorotetrakis (dimethylphenyl phosphino) ditechnetium (II) by an Aminium Hexachloroantimonate (N)."
 
 

Hinze, Willie L.

(with Dai, Fang; Burkert, Vera Prelevic; Singh, Hernandon N.) "Update and Evaluation of the Effectiveness of Different Thiols and Micellar Media in Roth's Fluorimetric Method for the Determination of Primary Amino Compounds." Microchemical Journal, 57 (1997) 166-198.

(with Nair, Usha B., Armstrong, Daniel W.) "Characterization and Evaluation of d-(+)-Tubocurarine Chloride as a Chiral Selectro for Capillary Electrophoretic Enantioseparations." Analytical Chemistry, 70 (1998) 1059-1065.
 
 

Jones, Bradley T.

(with Rhoades, C.B., Kevine K., Salido A.) "Clean chemistry for elemental analysis using microwave digestion and an environmental evaporation chamber." Appl. Spectrosc. 52 (1998) 200-204.

(with Shepard, M.R., Butcher, D.J.) "High resolution time-resolved spectra of indium and aluminum atoms, fluorides, chlorides, and oxides in a graphite furnace." Appl. Spectrosc. 52 ( 1998) 430-437.

"Inductively Coupled and Microwave Induces Plasma Sources for Mass Spectrometry, A Book Review." Microchem. J. 58 (1998) 236.

(with Besecker, K.D., Rhoades, C.B. Jr., Barnes, K.W.) "A Simple Closed-Vessel Nitric Acid Digestion Method for a Polyethylene/polypropylene Polymer Blend." Atomic Spectroscopy 19(1) 1998 in press.

(with Besecker, K.D., Rhoades, C.B., Jr., Barnes, K.W.) "A Simple Closed-Vessel Nitric Acid Digestion Method for Cosmetic Samples." Atomic Spectroscopy 19(1) (1998) in press.

(with Besecker, K.D., Rhoades, C.B., Jr., Barnes, K.W.) "Closed -Vessel Nitric Acid microwave digestion of polymers." Atomic Spectroscopy 19(1) (1998) in press.
 
 

King, S. Bruce

(with D. B. Kim-Shapiro, Bonifant, C.L., Kolibash, C.P., Ballas, S.K.) "Time Resolved Absorption Study of the Reaction of Hydroxyurea with Sickle Cell Hemoglobin." Biochimica et Biophysica Act, 1380 (1998) 64-74.

Chemistry Department Seminar, University of North Carolina at Greensboro, January 30, 1998.

Chemistry Department Seminar, Claflin College, Orangeburg, SC, February 14, 1998.
 
 

Kondepudi, Dilip K.

(with Prigogine, I.) Modern Thermodynamics: From Heat Engines to Dissipative Structures.  John Wiley, New York, 1998.

(with Culha, Mustafa) "Chiral Interaction and Stochastic Interaction in Stirred Crystallization of Amino Acids." Chirality 10 (1998) 238-245.

(with Prigogine, I.) "Nonequilibrium Thermodynamics" Encyclopedia of Applied Physics. Vol. 21 (VCH Publisher, Inc. New York, 1997).
 
 

Manderville, Richard A.

"Ochratoxin A acts as a photoactivatable DNA cleaving agent." Chem. Commun., (1998) 647-648.

"Copper-Mediated Nuclease activity of a tambjamine alkaloid." J. Am. Chem. Soc. (1998), to appear in May 27 issue.

"On the role of iron and copper in DNA cleavage by Ochratoxin A." Can. J. Chem., (1998), to appear in the June issue.
 
 

Welker, Mark E.

(with Adams, Torrey A. and Day Cynthia S.) "Transition-Metal Mediated Dihydropyran Syntheses. Exo Selective Hetero Diels-Alder Reactions of Cobaloxime Dienyl Complexes with Aldehydes." J. Org. Chem. 63 (1998) in press.

(with Hurley, Allison L., and Day, Cynthia S.) "Reactions of Transition-Metal h1-Allenyl Complexes with Sulfur Dioxide and Transition-Metal-Carbon Bond Cleaving Reactions of the Cycloadducts Which Yield Cyclic Sulfenate Esters". Organometallics 17 (1998) in press.

(with Patel, Paren, Liable-Sands, Louise M., and Rheingold, Arnold L.) "Preparation of Chiral at Iron Substituted Allyl and Vinyl Sulfones. Subsequent Enolate Generation and Stereo and Regioselective Alkylation". Organometallics 16 (1997) 4519.

(with Adams, Torrey A.) "Synthesis of Cobaloxime Substituted, a, b-Unsaturated Acyl Complexes via Reactions of Cobaloxime Anions and/or Hydrides with Ynones, Ynoates and a, b-unsaturated Acyl Electrophiles". Organometallics, 16 (1997) 1300.

(with Chapman, John J.) "Preparation of Cobalt (III) Salen-1,3-Butadien-2-yl Complexes and Their Utilization in Facile and Regioselective Diels-Alder Reactions". Organometallics 116 (1997) 747-755.

(with Richardson, B. Matthew) "Transition-Metal Mediated Exo Selective Diels-Alder Reactions Used in the Preparation of Octalones with Unusual Stereochemistries". J. Org. Chem. 61 (1997) 1299.

(with Patel, Paren P.) " Preparation of h5-Cyclopentadienyl and h5-Methylcyclopentadienyl)FeCO)2ME Cyclodextrin Inclusion Compounds and Their Subsequent Ligand Substitution Reactions. Attempts at Cyclodextrin Mediated Enantioselective Ligand Substitution". J. Organometal. Chem 547 (1997) 103-112.

(with Wright, Marcus W., Stokes, Heather L., Richardson, B. Matthew, Adams, Torrey A., Smalley, Terrence L., Vaughn, Stacia P., Lohr, Ginger L., Liable-Sands, Louise, Rheingold, Arnold L.) "Preparation and Exo Selective 4 + 2 Cycloaddition Reactions of Cobaloxime Substituted 1,3-Dienes". Invited Review (Book Chapter) Advances in Cycloaddition, Lautens, M., Ed. JAI Press, Greenwich, Conn. 4, (1997) 149-206.
 
 

II. Papers and Presentations
 
 

Colyer, Christa L.

Presentation: (with Moody, E.D., Viskari, P.J.) "Indocyanine green-protein complexes in capillary electrophoresis with laser-induced fluorescence detection". 15th Triangle Chromatography Symposium, Raleigh, NC, May 14, 1998.
 
 

Haefner, Steven C.

(with C. S. Day) "Pyridyl Substituted Formanidinates as Ligands for Building Extended one-dimensional Metal Clusters". Gordon Research Conference on Inorganic Chemistry, Newport, RI, July 1997.

(with C. S. Day) "Pyridyl Substituted Formanidinates as Ligands for Building Extended one-dimensional Metal Clusters". 49th ACS Southeast Regional Meeting, Roanoke, VA, October 1997.
 
 

Hegstrom, Roger A.

Presentation: "Spontaneous Symmetry Breaking in Bose-Einstein Condensates". Gordon Research Conference on Atomic Physics, New England College, June 29-July 4, 1997.
 
 

Hinze, Willie L.

Presentation: "Characterization of Micelle-Mimetic Ionene Polyeletrolyte-Silica Gel Stationary Phases for Chromatographic Separation" and "Review and Update on Applications of Surfactant-Mediated Phase Separations (Cloud Point Extractions)". American Chemical Society National Meeting, Dallas, TX, March 29-30, 1998.

Presentation: "Characterization and Evaluation of d-(+)-Tubocurrarine Chloride as a Chiral Selector for Capillary Electrophoretic Enantioseparations" and "Effectiveness of Micelle-Mimetic Ionene Polyelectrolyte Stationary Phases for High Performance Liquid Chromatography". High Performance Liquid Chromatography '98 Symposium, St. Louis, M0, May 3 and 6, 1998.
 
 

Jones, Bradley T.

Presentation: "Development of a portable tungsten coil atomic absorption spectrometer". Invited seminar presented at Leeman Labs, Inc., Lowell, MA, May 7, 1997.

Presentation: "An inexpensive CCD spectrometer for educational and research laboratories". UNC-G Greensboro, NC, September 12, 1997.

Presentation: (with Batchelor, J.D., Salido, A.L.) "A portable tungsten coil atomic absorption spectrometer". Federation of Analytical Chemistry and Spectroscopy Societies" (FACSS), Providence, RI, October 1997.

Presentation: (with Wagner K.A.) "Simultaneous multi-element GF-AAS using a rowland circle spectrometer with CCD detection", Federation of Analytical Chemistry and Spectoscopy Societies (FACSS), Providence, RI, October 1997.

Presentation: (with Levine, K.E., Wagner, K.) "Simultaneous multi-element determination of trace metals using inexpensive tungsten coils for electrothermal vaporization ICP/AES", Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Providence, RI, October 1997.

Presentation: (with Salido, A.L.) "Development of a multi-element W-coil spectrometer for simultaneous determination of Cu, Pb, and Cd", Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Providence, RI, October 1997.

Presentation: (with Batchelor, J.D.) "In the field determinations of Cd with a portable tungsten coil atomic absorption spectrometer", Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Providence, RI, October 1997.

Presentation: (with Daniel, M.M., Batchelor, J.D.) "Trace metal analysis of water using solid phase extraction disks and x-ray fluorescence spectrometry". Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Providence, RI, October 1997.

Presentation: (with Wagner, K.) "Multi-element atomic absorption spectrometry with a tungsten coil atomizer". Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Providence, RI, October 1997.

Presentation: (with Batchelor, J.D.) "Development of an atomic spectrometer based upon a digital micromirror device (DMD)" Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Providence, RI, October 1997.

Presentation: (with Besecker, K.D.) "Optimization of acid digestion temperatures using high performance liquid chromatographpy". Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Providence, RI, October 1997.

Presentation: (with Mantooth, B., Canford, C.L.) "Modular instrumentation design: Part I. Raman Spectroscopy". Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), Providence, RI, October 1997.

Presentation: (with Bostick, R., Ennever, B. Shelton, Case, D., Zaccaro, D., Fleming, R., Swarts, S., Vitolins, M. "Urinary Cadmium and Risk for Incident Prostate Cancer, "22nd Annual Meeting of the American Society of Preventive Oncology, Bethesda, MD, March 4-6, 1998.

Presentation: (with Salido, A.L.) "Development of a Blood-Pb AA Spectrometer," New Orleans, LA, March 1998.

Presentation: (with Levine, K.E.) "Simultaneous Multi-element Determinations of Trace Metals Using Inexpensive Tungsten Coils for Electrothermal Vaporization ICP-AES", New Orleans, LA, March 1998.

Presentation: (with Batchelor, J.D.) "Development of a Digital Micromirror Based Spectrometer", New Orleans, LA, March 1998.

Presentation: (with Wagner, K.A.) "Multi-element Atomic Absorption Spectrometry with a Tungsten Coil Atomizer", New Orleans, LA, March 1998.

Presentation: (with Daniel, M.M., Batchelor, J.D.) " Examination of Acid Digestates by HPLC and LC-MS", New Orleans, LA, March 1998.
 
 

King, Angela G.

Presentation: "Replacing Traditional Writing Assignments with Web-Page Development". SERMACS, October 1997.

Presentation: "Designing Science Outreach to Meet Goals". ACS National Meeting, March 1998.

Presentation: "Getting Started In Chemical Education Research" ACS National Meeting, March 1998.

Presentation: "What Learning Difference Results from Ubiquitous Computing?" ICCEI, April 1998.
 
 

King, S. Bruce

Presentation: (with Atkinson, R.N.) "Synthesis and Evaluation of Conformationally Restricted Aromatic L-Amino Acids Designed to Interact with Nitric Oxide Synthase". Abstract of Papers, 215th National Meeting of the American Chemical Society, Dallas, TX, American Chemical Society, Washington, DC, 1998, MEDI 72.

Presentation: (with Palmer, E.C., Alavanja, M.M., Yasaki, Y.) "Retro Diels Alder Reactions of C-Nitrosoformamide-9,10 Dimethylanthracene Cycloadducts: Production of Nitroxyl (HNO)," Abstracts of Papers, 49th Southeast Regional Meeting of the American Chemical Society, Roanoke, VA; American Chemical Society: Washington, DC, 1997, ORGN 362.

Presentation: (with Ware, R.W., Jr., Xu, Yueping, Bonifant, C.L., Kim-Shapiro, D.B.) "Chemical Oxidation of Hydroxyurea". Abstracts of Papers, 49th Southeast Regional Meeting of the American Chemical Society, Roanoke, VA; American Chemical Society: Washington, DC, 1997, ORGN. 154.

Presentation: (with Atkinson, R.N.) "Syntheses and Evaluation of L-Arginine Derivatives Designed to Interact with Nitric Oxide Synthase" Abstracts of Papers, 49th Southeast Regional Meeting of the American Chemical Society, Roanoke, VA; American Chemical Society: Washington, DC, 1997, ORGN 154.
 
 

Kondepudi, Dilip K.

Presentation: "The role of randomness in Chemical Reactions". University of Texas at Austin, April 2, 1998. (Invited talk.)
 
 

Manderville, Richard A.

"Copper-Mediated DNA Damage by Ochratoxin A." Talk presented at SERMACS-97, Roanoke, VA, October 19-22, 1997.
 
 

Noftle, Ronald E.

Paper: "Mechanistic Aspects of the Formation of Conducting Polymers and the Synthesis of Imide Monomers" Portland State University.

Presentation: (with Dai, J; Gard, G.L.) "Preparation and Properties of Thiophenes Containing Fluorinated Groups". E., Internat. Symposium on Fluorine Chemistry, Vancouver, BC Canada, August 2-7, 1997. Invited Presentation.

Presentation: (with Narula, P.M.) "Electrochemical Studies of the Oxidation of 3-Substituted Pyrroles", NC Academy of Sciences Annual Meeting, N. C. Central University, Durham, NC, March 23, 1997.

Presentation: (with Calcutt, M.W., Narula, P.M., Adrus, J.A., Gillman, I.G., Manderville, R.A., "Electrochemical Oxidation of Ochratoxin A. Implications for a Quinone Metabolite. Forty-Ninth Annual Southeast Regional Meeting of the Am. Chem. Soc., Roanoke, VA, October 19-22, 1997.

Presentation: (with Sellers J.L.) "Studies of Platinum Electroplating Baths. The Electrochemistry of cis-PtC12R2 and trans-PtC12R2 in Acid Media. Forty-Ninth Annual Southeast Regional meeting of the Am. Chem. Soc, Roanoke, VA, October 19-22, 1997.

Presentation: (with Dai, J., Gard, G.L.) "Preparation and Properties of Thiophenes Containing Fluorinated Groups". Forty-Ninth Annual Southeast Regional meeting of the Am. Chem. Soc, Roanoke, VA, October 19-22, 1997.

Presentation: (with Dai, J.) "Synthesis and Characterization of 3-Thenoyl Imides". North Carolina Academy of Sciences Mtg., NCA&T Univ. Greensboro, NC, March 28, 1998.

Presentation: (with Calcutt, M.W., Gillman, I.G., Manderville, R.A.) "Electrochemistry of Ochratoxin A and Its Oxidatively Produced Derivatives", North Carolina Academy of Sciences Mtg., NCA&T Univ., Greensboro, NC, March 28, 1998.
 
 

Swofford, Robert L.

Presentation: "Wake Forest's Computer Plan for the Class of 2000". S.E. Regional American Chemical Society Meeting, October 1997.
 
 

Welker, Mark E.

Presentation: NSF Organometallic Chemistry Workshop, Knoxville, TN, June 11-14, 1998.

Presentation: Departmental Seminar, University of Virginia, Charlottesville, VA, April 3, 1998.

Presentation: Second UNCW Symposium on Chemistry & Biochemistry, UNC-Wilmington, January 30-31, 1998. One of twelve invited speakers nationally.

Presentation: Cellular Defense & DNA Damage Program Retreat of the Comprehensive Cancer Center of Wake Forest University, December 15, 1997.

Presentation: Organometallics in Organic Synthesis Symposium Speaker, 5th Chemical Congress of North American, Cancun, Mexico, November 15, 1997.

Presentation: Roche Carolina Symposium on Trends in Organometallic Chemistry Roche Pharmaceuticals, Florence, SC, October 28, 1997. One of the 5 invited speakers nationally.

Presentation: Departmental Seminar, Appalachian State University, October 3, 1997.
 
 

III. Editorships, Offices and Consultancies
 
 

Colyer, Christa C.

Invited member: Committee on Scholarships & Fellowships, Natural Sciences and Engineering Research Council of Canada (NSERC).
 
 

Hinze, Willie L.

Editorial Board, Analytical Letters.

Editorial Board, Talanta.

Editorial Board, Journal of Liquid Chromatography.

Editor, JAI Press, Inc. yearly series on Organized Assemblies in Chemical Analysis.

President, North Carolina Institute of Chemists.

Commissioner, National Certification Commission in Chemistry & Chemical Engineering of the American Institute of Chemists.
 
 

Jones, Bradley T.

R J Reynolds Tobacco Co. (2 months).
 
 

King, Angela G.

Editorial Board, Interactive Multimedia Electronic Journal.

Wm. C. Brown, Publishers, ca. 10 hr/summer.
 
 

Kondepudi, Dilip K.

Editorial Board, Chirality.

Reviewed grant proposals for National Science Foundation.
 
 

Noftle, Ronald E.

Executive Committee and Alternate Councilor, Division of Fluorine Chem., Am. Chem. Soc.

Marshallton Laboratories (6 hours per year).
 
 

Swofford, Robert L.

International Center for Computer-Enhanced Learning - 1 day.
 
 

Welker, Mark E.

Referee/Reviewer for: Journal of the American Chemical Society; Journal of Organic Chemistry; Tetrahedron; Tetrahedron Letters; Tetrahedron Symposia-in-Print; Chemica Reviews; Organometallics; Journal of Organometallic Chemistry; Synthesis Letters; Inorganica Chimica Acta; Journal of the Royal Chemical Society, Dalton Transactions.

National Science Foundation.

Petroleum Research Fund.

Research Corporation.

NIH NIGMS Medicinal Chemistry Study Section Ad Hoc Reviewer (1994).

NSF Postdoctoral Fellowship Panel Reviewer (Organic Synthesis) (1995).

Montana EPSCOR Program.

External Dissertation Reviewer: University of Poona, Pune, India, SUNY- Buffalo (2).

External Tenure Reviewer: Washington State University, Ohio University, New Mexico State University, UNC-Charlotte.

Consultant, John Wileys & Sons, Publishers.

Consultant, Prentice-Hall Publishers.

Consultant, Jones & Bartlett Publishers.
 
 

IV. External Grants Received
 
 

Fishbein, James C.

$520,000.00.  Nitrosamine Carcinogenesis.

$150,000.00.  "Acquisition of a 400 MHz NMR Spectrophotometer". (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NC Biotechnology Center.

$219,000.00. "Purchase of a 400 MHz NMR Spectrometer" (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NSF.
 
 

Haefner, Steven C.

$150,000.00.  "Acquisition of a 400 MHz NMR Spectrophotometer". (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NC Biotechnology Center.

$219,000.00.  "Purchase of a 400 MHz NMR Spectrometer" (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NSF.
 
 

Hegstrom, Roger A.

$150,000.00.  "Acquisition of a 400 MHz NMR Spectrophotometer". (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NC Biotechnology Center.

$219,000.00. "Purchase of a 400 MHz NMR Spectrometer" (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NSF.
 
 

Hinze, Willie L.

$3,712.50. "Evaluation of Bonded Ionenes as Stationary Phase Materials for Liquid Chromatography and Solid Phase Exctractions". Advanced Separation Technologies, Inc.
 
 

Jones, Bradley T.

$20,000.00.  "Development of a Portable Blood-Pb Analyzer". Leeman Labs, Inc.

$89,000.00.  "TRACE, Trace-metal Research and Collaborative Education".  NSF-GOALI.

$96,250.00.  "An Inexpensive reliable Blood-Pb Analyzer". NIH-STTR.

$30,000.00.  "An ICP Spectrometer for Undergraduate Chemistry Laboratory Courses".  Sam Booke.
 
 

King, S. Bruce

$20,000.00.  "N-Phosphinolhydroxylamines as New Nitric Oxide and Nitroxyl Delivery Agents". American Chemical Society/Petroleum Research Fund.

$150,000.00.  "Acquisition of a 400 MHz NMR Spectrophotometer". (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NC Biotechnology Center.

$219,000.00.  "Purchase of a 400 MHz NMR Spectrometer" (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NSF.
 
 

Kondepudi, Dilip K.

$6,670.00 "Crystallization of Citalopram" Forest Labs.
 
 

Manderville, Richard A.

$20,000.00.  "Synthesis of Tambjamine Alkaloids and Polypyrroles as DNA Sensors. Petroleum Research Fund, American Chemical Society.

$150,000.00.  "Acquisition of a 400 MHz NMR Spectrophotometer". (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NC Biotechnology Center.

$219,000.00.  "Purchase of a 400 MHz NMR Spectrometer" (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NSF.
 
 

Noftle, Ronald E.

$150,000.00.  "Acquisition of a 400 MHz NMR Spectrophotometer". (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NC Biotechnology Center.

$219,000.00.  "Purchase of a 400 MHz NMR Spectrometer" (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NSF.

$5,880.00.  "Synthesis and Characterization of Novel Thiophenes With Main Group Substituents". RECREAC.
 
 

Welker, Mark E.

$227,500.00.  "Exo Selective and Enantioselective Transition Metal Mediated Cycloaddition Reactions". National Science Foundation.

$107,670.00.  "Synthesis of Potential Anticarcinogenic Enzyme Inducers". National Institutes of Health.

$60,000.00.  "Henry Dreyfus Teacher Scholar Award". Camille and Henry Dreyfus Foundation.

$150,000.00.  "Acquisition of a 400 MHz NMR Spectrophotometer". (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NC Biotechnology Center.

$219,000.00.  "Purchase of a 400 MHz NMR Spectrometer" (co-PI with Hegstrom, Welker, Fishbein, Noftle, King, Manderville, Haefner). NSF.