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Ulrich Bierbach
Associate Professor

Diplom (Chemistry), 1989, University of Oldenburg, Germany
Ph.D., 1992, University of Oldenburg, Germany (S. Pohl)
Postdoctoral Fellow (German Research Council, DFG), 1992–1993, Leiden University, The Netherlands (J. Reedijk)
DFG Research Fellow, 1994–1996, Virginia Commonwealth University (N. Farrell)
Research Associate, 1996–1998, Virginia Commonwealth University (N. Farrell)
Postdoctoral Research Associate, 1998–1999, University of Minnesota (L. Que, Jr.)
 

E-Mail Me
Phone: (336) 758-3507
Home Page: http://www.wfu.edu/academics/bierbachgp/
Research Details

Click here for the Chemistry Graduate Program Online Inquiry Card

Description of Research
Research in our laboratory is concerned with the design of small-molecule agents for the cure and management of life-threatening diseases and for probing and modulating gene regulation. Structurally novel drugs and drug conjugates are prepared using organic and inorganic synthetic methodologies. The interactions of these agents with potential biomolecular targets (DNA, DNA-processing enzymes, metalloenzymes) are studied using bioanalytical (LC-MS) and high-resolution structural (NMR, X-ray) methods, as well as biophysical and molecular biology techniques. Biological activity studies are carried out in vitro and in vivo by collaborators at WFU School of Medicine. Our research is funded through the National Institutes of Health.
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Address (campus map): Chemistry Department, Wake Forest University, Salem Hall, Box 7486
Winston-Salem, NC 27109. Phone: (336) 758-5325 FAX: (336) 758-4656
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